Scorpion and spider venoms in cancer treatment: state of the art, challenges, and perspectives

Radiolabeling the Peptides extracted from Scorpion venom (ICD-85) with 99mTc as treatment and imaging agent for cancer

Introduction: Venoms are a mixture of proteins and peptides which can be used for fighting cancers. They can affect the exposed fibers and the muscles directly or through motor nerves, causing neuromuscular intoxication. ICD-85 is a combination of three poly-peptides derived from the venoms of an Iranian brown snake and a yellow scorpion. Materials and Methods...

Radioiodination of a natural toxin (ICD-85) for fighting cancer

Introduction: Many molecules can be labeled by iodine. Some of labeled substances are used for investigations of cancer treatment, biodistribution study in body, receptor binding, secrete pathway etc. Peptides are biomolecules and can be labeled by 131Iodine. ICD- 85 is a tri-peptide derived from Iranian brown snake venom and scorpion venom. This tri-peptide treats cancer by i...

Study on Specific and Nonspecific Effects of Antivenoms of Andrctonus crassicauda, Buthotus saulcyi and Odontobuthus doriae Against Venoms of Important Species of Scorpion in Iran

Membrane Science and Research in Asia and the Middle East: State of the Art and Perspectives

Asia and Middle East represent one of the most dynamic regions in the world which has experienced fast economic and technological growth. Access to clean and affordable water is essential for building resilience and maintaining human’s well-being and livelihood development in this region. Likewise, various energy resources are fundamental to support stable economic and social progress for bette...

Neutralization Capacity of Monovalant Antivenom Against Existing Lethal Scorpions in The Turkish Scorpiofauna

In this study, Mesobuthus gibbosus and Mesobuthus eupeus eupeus venom samples were compared for lethality, in vivo effects and proteins. Neutralization capacity of monovalent Androctonus crassicauda antivenom (RSHA anti-Ac) was tested against the lethal effects of the venoms.Venom was obtained from mature scorpions by electrical stimulation of the telson. The lethality of the venom and potency ...